| abstract |
(57) [Summary] [Objective] To provide a process for producing diaceline in high yield and free of impurities Aloe emodin mutagenic component. [Structure] The production process of 1,8-diacetoxy-3-carboxyanthraquinone (diacereine) is obtained by acetylation of aloin, oxidation of acetylated product, and crystallization from 2-methoxyethanol or N, N-dimethylacetamide. Purification of unpurified diaceline, And optionally dissolving the corresponding salt with triethylamine in methylene chloride, removing the insoluble residue. |