abstract |
(57) [Summary] [Composition] Immune cells, endothelial cells or both (A) an antibody or a binding site-containing fragment thereof that specifically binds to ELAM cells, and (b) VCAM, ELAM, I CAM, VCAM ligand, ELAM ligand and IC A method for regulating an immune response, which comprises binding an antibody or a binding site-containing fragment thereof that specifically binds to a molecule selected from the group consisting of AM ligands; and (A) an antibody that specifically binds to an ELAM molecule, or A binding site-containing fragment, or a pharmaceutically acceptable salt of the antibody or fragment (B) that specifically binds to at least a molecule selected from the group consisting of VCAM, ELAM, ICAM, VCAM ligand, ELAM ligand and ICAM ligand Immune cells and endothelial cells comprising one antibody, or a binding site-containing fragment thereof, or a pharmaceutically acceptable salt of the antibody or fragment and (C) a pharmaceutically acceptable carrier, diluent or excipient [Effect] Various diseases can be treated without side effects by specifically regulating the immune response. |