| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afd115dec46c157d3739020ebd4d866b |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745 |
| filingDate |
1993-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e496644bc10d977d9d528e98f5cf506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9c22c6c9421527fab589d8399234787
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3f056b42cd738e73423aee2e3f048da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e94ee32c683ba47d43865e8ab560433d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8844a60e584144f9768575d707d1268a |
| publicationDate |
1995-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H0733799-A |
| titleOfInvention |
High specific activity thrombin and method for producing the same |
| abstract |
(57) [Summary] [Structure] Thrombin having a specific activity of 1000 units / A 280 or more. A method for producing thrombin by subjecting prothrombin to thrombin in the state of a prothrombin complex, particularly a method for producing thrombin by treating with a cation exchanger after the treatment. [Effect] Thrombin produced by the method is It has a high specific activity of 1000 units / A 280 and is extremely useful as a thrombin preparation. Further, the thrombin is stable in a cold state for a long period even in a solution state. Therefore, the method of the present invention is extremely practical as a method for producing thrombin, and the obtained purified thrombin can be clinically used as a useful drug. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001327592-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5811279-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6611343-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1063789-C |
| priorityDate |
1993-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |