| abstract |
(57) [Summary] [Structure] Formula [Chemical Formula 24] Or [Chemical 28] [R-COO and OOC-R'-COO are the alcoxy residues of monocarboxylic sun and dicarboxylic acid, respectively, which have bioinfluence, and R 1 , R 2 and R 3 each represent a monovalent residue? , Or R 1 and R 2 are bonded to each other- NR 1 R 2 represents a residue of a saturated or unsaturated heterocyclic compound containing one secondary nitrogen atom. ] The non-toxic pharmaceutically acceptable acid addition salt and N-oxidized form of the compound represented by these, and the compound of said general formula (I) and (II). Efficacy: This compound elicits a bio-affecting (eg pharmacological) response characteristic of the original acid induced when administered to warm-blooded animals, resulting in better biphasic dissolution. It is characterized as an active substance, is less irritating than the parent compound, and has excellent permeability to biological membranes such as skin, intestine, buccal or rectal mucosa. |