abstract |
(57) [Summary] (Modified) [Objective] Specific binding to human IL-2 receptor γ chain and selective inhibition of binding between human IL-2 receptor γ chain and IL-2 receptor β chain And a polypeptide having an activity of blocking an IL-2 response, an immunosuppressive agent containing the polypeptide, a gene encoding the polypeptide, Provided are a recombinant DNA having the gene, a transformant having the recombinant DNA, and a method for producing the desired polypeptide by culturing the transformant. [Structure] Activity that specifically binds to human IL-2 receptor γ chain, selectively inhibits binding between human IL-2 receptor γ chain and IL-2 receptor β chain, and blocks IL-2 response A polypeptide having, an immunosuppressive agent containing the polypeptide, a gene encoding the polypeptide, A recombinant DNA having the gene, a transformant having the recombinant DNA, and a method for producing the desired polypeptide by culturing the transformant. |