| abstract |
(57) [Summary] [Object] To provide a therapeutic agent for thrombocytopenia useful as a medicine and a novel indolocarbazole derivative useful as a component thereof. [Structure] General formula (I) {Wherein R 1 is hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl or tetrahydropyranyl, and R 2A and R 3A are the same or different and are hydrogen, substituted or unsubstituted lower alkyl, A lower alkenyl, a substituted or unsubstituted aralkyl or monosaccharide residue excluding an anomer hydroxyl group, R 4A and R 5A are the same or different and each is hydrogen, formyl, hydroxy or halogen, and W A is hydrogen (2 atoms ) Or oxygen, X A may be hydrogen without forming a bond, hydrogen, or may form a bond. However, when X A forms a bond, R 1 , R 2A , R 3A , R 4A , R 5A and W A are not simultaneously hydrogen. } The therapeutic agent for thrombocytopenia containing the indolocarbazole derivative represented by the formula or a pharmacologically acceptable salt thereof as an active ingredient. |