| abstract |
(57) [Summary] [Objective] To provide a drug having a strong antagonism with a higher selectivity for muscarinic receptors of other smooth muscles than that of cardiac muscarinic receptors. [Configuration] The following general formula (1) (In the formula, R 1 and R 2 each represent an unsubstituted or optionally substituted phenyl group or pyridyl group, R 3 represents a hydrogen atom or a lower alkyl group, and R 4 and R 5 are the same. or different and each represents a hydrogen atom, a lower alkyl group, further R 4, R 5 may be crosslinked to form an alkylene ring, R 6, R 7 are the same or different and each represents a hydrogen atom, a lower It represents an alkyl group, an unsubstituted or optionally substituted phenyl group, R 8 represents a hydrogen atom, a halogen, a lower alkyl group, a lower alkoxy group, an alkylenedioxy group, and m represents 1 to 4. , N is 1 to 3 And p represents 0 to 3. And a pharmaceutically acceptable salt thereof, and a method for producing the same. |