| abstract |
(57) [Summary] [Object] The present invention aims to obtain an antitumor agent with few side effects on the human body. [Structure] An antitumor agent containing hydroxylinoleic acid as an active ingredient. An antitumor agent containing hydroxylinoleic acid as an active ingredient, which is obtained by reacting linoleic acid with plant lipoxygenase. Plant lipoxygenase was added to linoleic acid to react, the pH of this reaction solution was adjusted, the precipitate was filtered, the organic solvent was added and the extract was concentrated under reduced pressure, and then applied to a silica gel column with a suitable eluent. Weigh out aliquots, A method for producing an antitumor agent, which comprises subjecting each fraction to thin layer chromatography, collecting and precipitating a fraction of hydroxylinoleic acid, and drying the precipitate under reduced pressure. |