| abstract |
(57) [Summary] (Modified) [Object] To provide an intermediate compound represented by the formula (XVIIa), which is useful for the production of a pyranylcyanoguanidine derivative. The intermediate compound of the present invention has the formula (I), the formula (II It is a pyrano [4,3-d] oxazole derivative represented by I) or the like. [Wherein a, b and d are all C or one of them is N; R 1 and R 2 are hydrogen, alkyl, aryl, cycloalkyl or the like or a nitrogen atom to which they are bonded; 1-pyrrolidinyl, 1-piperidinyl and the like, R 3 and R 4 are hydrogen, alkyl, arylalkyl, or 5 to 5 together with the carbon atom to which they are bonded. It represents 7-membered ring; R 5 represents hydrogen, alkyl, cyano, nitro or the like; R 6 is hydrogen, alkyl, -OH, -NH 2, It represents -CN or the like; R 9 is hydrogen, alkyl, aryl or the like; R 10 is a group -N (R 12) -C (= N-CN) - NR 1 R 2 (provided that R 12 is hydrogen, alkyl, aryl, etc.); R 11 represents hydrogen, —OH, —OCOCH 3 ; n is an integer of 1 to 3] |