| abstract |
(57) [Summary] [Structure] General Formula (I) [In the formula, each symbol is as described in the description. ] A prophylactic / therapeutic agent for thromboxane A 2 -related diseases, which comprises a pyridazinone compound represented by the following formula or a pharmacologically acceptable salt thereof as an active ingredient, particularly a thromboxane A 2 synthase inhibitor. EFFECT pyridazinone compound in the present invention (I) and its pharmacologically acceptable salts, prophylactic and therapeutic action of TXA 2 mediated diseases, and in particular a TXA 2 synthase inhibitory activity, TXA 2 mediated diseases Preventive / therapeutic agent, especially TX It is useful as an A 2 synthase inhibitor. |