http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H07284390-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14effe3850d2129f863b969dac4f1db8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-743 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
filingDate | 1993-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccad9ac6a239ffd2b41095c8f90bcfcc |
publicationDate | 1995-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H07284390-A |
titleOfInvention | Development of a mechanism-based screen for identifying agonists and antagonists of the androgen receptor |
abstract | (57) [Summary] [Construction] An agonist or antagonist of an androgen receptor, which comprises screening a superfamily antagonist of a steroid / thyroid receptor using a mouse androgen receptor expressed by a yeast expression system. For expressing a series of mutant androgen receptors expressed in a yeast expression system; analyzing the binding activity of an antagonist or agonist hormone binding to the expressed receptors; binding of mutant receptors A method for determining the functional site of an androgen receptor, which comprises comparing the activity to a known functional receptor region; and determining the transcriptional activation domain of the mouse androgen receptor. Efficacy The use of this yeast system enhances the ability to screen for steroid thyroid receptor superfamily agonists and / or antagonists and further allows localization and identification of androgen receptor functional domains. . |
priorityDate | 1992-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 308.