abstract |
(57) [Summary] (Modified) [Structure] A carbohydrate mimic represented by formula I, a method for producing the same, and a drug containing the compound. [In the formula, R 1 and R 2 are H, CH 3 , CH 2 NH 2 , and CH. 2 OCH 2 CH 2 OH, etc., or together form a 6-membered carbocycle or heterocycle having a substituent such as NH 2 , OH; R 3 is O, S, H, CH 2 OH, etc. R 4 , R 5 and Y are O-α (or β) -N-acetylneuraminic acid, O- (CH 2 ) n- COOH and the like; R 6 is a hydroxyl group or an alkoxy group, or Forms a 6-membered carbocyclic or heterocyclic ring together with R 3 ; Z is pyranose, furanose or an open chain polyalcohol; n is a number from 1 to 20] [Effect] This compound has anti-adhesion properties and prevents diseases such as infectious diseases, inflammatory processes and metastatic tumors. -Used in the manufacture of medicines for treatment. |