abstract |
(57) [Abstract] [Purpose] Isolated non-A non-B hepatitis virus (NAN) BV) Provision of particles and their production. Disclosed is a NANBV particle consisting of at least one antigen selected from C antigen, M antigen and E antigen, and efficient production of the particle by a genetic engineering technique, thereby exhibiting a high degree of immunogenicity. Practical application of non-A non-B hepatitis vaccine, provision of diagnostic agents with high antibody positive rate and detection accuracy, and provision of non-A non-B hepatitis virus particles and genes useful as research materials for liver diseases and liver cancer It will be possible. |