| abstract |
(57) [Summary] [Structure] Formula I: Wherein PG is a weak acid labile urethane or trityl amino protecting group, X is NH, O or S, Y is CH 2 , NH or O, and B ′ is nucleotide chemistry. A conventional base, provided that its exocyclic amino or hydroxyl group is protected by a suitable known protecting group, or is a base-substituted compound] and an N-ethylglycine derivative t -Its salt with an organic base. Effect The N-ethylglycine derivative of formula I is used as a reagent in the production of PNA and PNA / DNA hybrids. |