| abstract |
(57) [Summary] (Modified) [Objective] To provide a novel cytotoxic compound, a method for producing the same, and a method for using the same. [Structure] General formula VIIa Cytotoxic anti-tumor 8-hydroxy-bicyclo [7.3.1] tridec-4-ene-2,6 -Diyne ring compounds, a novel method for producing the same, and a therapeutic agent for malignant tumor thereof. Koba Specific examples of the compounds of the general formula VIIa is Hexacarbonyl [μ-[(6,7- n ) -1- [[(1,1-Dimethylethyl) dimethylsilyl] oxy Ci] -8-Hydroxy-10-phenylthiobicyclo [7.3.1] Tridec-4-ene-2,6-diyne- 13-on]] Di (Co-Co) . |