| abstract |
(57) [Summary] [Structure] General formula [1] (In the formula, R 1 is an alkyl group or the like, R 2 is a carboxyl group or the like, R 3 is a halogen atom, an alkyl group or a phenyl group, and R 4 , R 5 and R 6 are each a hydrogen atom or a halogen atom or the like. R 7 is a carboxy group or a 5-tetrazolyl group, X Is a nitrogen atom or the like, Y and Z are CH or a nitrogen atom or the like, A And E means a methylene group or the like, D means a phenyl group or the like, and G means a covalent bond or the like. ] A pyrazole compound represented by Its tautomers and salts. [Effects] The compound of the present invention has an antagonistic action against angiotensin II, and is useful for the prevention and treatment of hypertension, congestive heart failure, chronic renal failure, aldosteronism, elevated intraocular pressure and the like. |