http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H07236477-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d75d1a4caed60a9316608ed9c231546c |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
filingDate | 1994-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a1cca0799e96c14aedf28ef6546ea1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2a29af88d9e2332ed9cb61226df05b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fa8fc6a16cbe6302e92ffd960853897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f647bf7ea7e1338b543e5d77595d0ac6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adb4bcf72a9d9bdc880b3f495a8da608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d267c82be3a015b66c04aa122c581a51 |
publicationDate | 1995-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H07236477-A |
titleOfInvention | Novel sugar chain synthase |
abstract | (57) [Summary] [Structure] The following receptor substrate specificity: disaccharide Galβ1,3G Use a glycolipid or glycoprotein having alNAc and Galβ1,3GalNAc at the end as a substrate; and the following receptor substrate selectivity: preferentially incorporate sialic acid into glycolipid in the presence of glycolipid and disaccharide , Gg4>GM1> G among glycolipids Galβ1,3GalNAc α2,3-sialyltransferase characterized by incorporating sialic acid in the order of D1b, and Galβ1,3GalNAc α2,3-sialyltransferase gene encoding the enzyme, and P-F4M and P -An extracellular secretory protein containing a polypeptide portion involved in F4R activity and a signal peptide, which catalyzes Galβ1,3GalNAc α2,3-sialyl transfer, and a method for producing the protein. [Effect] Galβ1,3GalNAc α2,3-sialyltransferase is effective in suppressing cancer metastasis, suppressing viral infection, suppressing inflammatory reaction, It is useful as a drug having a nerve cell activating effect, or as a reagent for increasing physiological action by adding sialic acid to the drug. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9913074-A1 |
priorityDate | 1994-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 684.