| abstract |
(57) [Summary] (Modified) [Structure] An external preparation for skin containing a water-soluble polymer and at least one or more amides of tranexamic acid represented by the following formula and salts thereof. Wherein, R 1 and R 2 are the same or different, a hydrogen atom, a linear or branched alkyl group having 1 to 18 carbon atoms, cycloalkyl group having 5 to 8 carbon atoms, a phenyl group, or R 1, And R 2 together represent a heterocyclic group of aziridine, azetidine, pyrrolidine, piperidine, hexahydroazepine, octahydroazocine or morpholine formed together with a nitrogen atom.] [Effect] Stable with a water-soluble polymer Despite its excellent properties, feeling of use, and moisturizing effect on the skin, it does not have the stickiness or slippery feeling peculiar to water-soluble polymers, and also has good safety. |