| abstract |
(57) [Summary] [Structure] An ultraviolet absorber and at least one of amides of tranexamic acid represented by the following general formula 1 and salts thereof. A skin external preparation characterized by containing at least one species. [Chemical 1] [In the formula, R 1 and R 2 are the same or different and each represents a hydrogen atom, a linear or branched alkyl group having 1 to 18 carbon atoms, a cycloalkyl group having 5 to 8 carbon atoms, or a phenylalkyl group (wherein the alkyl moiety is Has 1 to 3 carbon atoms, and the phenyl moiety may be substituted with 1 to 3 hydroxyl groups, lower alkyl groups, lower alkoxy groups, halogen atoms and amino groups), phenyl groups (wherein the phenyl group is 1 ~ 3 hydroxyl groups, a lower alkyl group, a lower alkoxy group, a halogen atom, an amino group may be substituted), or aziridine, azetidine, pyrrolidine formed by R 1 and R 2 together with a nitrogen atom, It shows a heterocyclic group of piperidine, hexahydroazepine, octahydroazocine or morpholine.] [Effect] The skin irritation of an ultraviolet absorber is suppressed and excellent skin is obtained. With the white effect. |