abstract |
(57) Abstract: (modified with) [Configuration] (2R, 4R)-4-methyl -l- [N 2 - ((RS) -3-Methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl) -L-arginyl] -2 An aqueous liquid preparation containing at least one argininamide selected from piperidinecarboxylic acid, its monohydrate and salts thereof, and at least one compound selected from cyclodextrin and caffeine. [Effect] The solubility of argininamide in water can be increased, and the concentration can be increased to a concentration at which the effect of inhibiting the formation of fibrin during intraocular surgery can be expected, and the stability of argininamide can be improved. Is increased and there is little eye irritation. |