| abstract |
(57) [Summary] [Objective] A novel antihyperlipidemic agent with low toxicity, which lowers blood cholesterol and inhibits macrophage foaming by inhibiting ACAT activity and intracellular cholesterol transport, and To provide an anti-atherosclerotic agent. [Structure] 5-chloro-1-dodecyl-2-methylbenzimidazole, 1-dodecanoyl-2-methylbenzimidazole, 2-ethoxycarbonylmethyl-1-tetradecanoylbenzimidazole, 1-dodecanoyl-2-mercaptobenzimidazole , An anti-hyperlipidemic agent and an anti-atherosclerotic agent which contain an analog compound thereof or a pharmaceutically acceptable salt thereof as an active ingredient. |