abstract |
(57) [Abstract] [Purpose] To improve the long-term storage stability of a packaged 1α, 24 (R) -dihydroxycholecalciferol oil-and-fat ointment for the treatment of psoriasis. [Structure] 1α, 24 ( R) -dihydroxycholecalciferol as an active ingredient, comprising a hydrophobic / anhydrous solvent such as a fatty acid ester such as diisopropyl adipate and a lipophilic base such as white petrolatum, and the amount of the solvent is 0.01 to The ointment is 25.0% by weight, and the material of the portion which comes into direct contact with the ointment is phenol-butyral resin or polystyrene resin, which is stored in a container. |