| abstract |
(57) [Summary] [Objective] A novel 1,2-dihydro-2-2 that has antagonistic properties against angiotensin II and can be used for the treatment of hypertension, hyperaldosterone and heart failure. Provided is oxo-3-methylsulfonylaminomethylpyridine and salts thereof. 1,2-Dihydro-2-oxo-3-methylsulfonylaminomethylpyridine has the general formula I: It is represented by. Where R 1 is alkyl having 1 to 5 C atoms, R 2 is CN or 1H-tetrazol-5-yl, and R 3 is alkyl having 1 to 5 C atoms. Or it is cyclopropylmethyl. |