Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14effe3850d2129f863b969dac4f1db8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-10 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 |
filingDate |
1993-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91daad9af150500eb9c84f64f514dd74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d38a21ce6a00fdce97869a4208beb872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc5c768294a28b5c4db978e9228502fe |
publicationDate |
1995-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H07173199-A |
titleOfInvention |
Compositions for the isolation of apamin receptors, apamin binding proteins and their use |
abstract |
(57) Summary: The present invention provides a composition comprising a free amino group covalently coupled to the free carboxyl group of apamin in a composition useful as an affinity matrix for isolating the apamin receptor from cellular material. A composition comprising a derivatized agarose matrix having: The present invention further contemplates a protein of about 80 KDa that is isolated from vertebrate tissue samples and specifically binds to apamin, and a protein of about 55 KDA that appears to be a degradation product of the protein, and the protein or its degradation products. Antibody that binds to the protein. The invention further relates to an isolated nucleic acid fragment comprising a nucleic acid sequence encoding an apamin receptor protein or a biologically active fragment thereof, and a host cell containing said nucleic acid fragment. [Effect] To obtain a means for identifying and separating compounds that may be therapeutically effective. |
priorityDate |
1992-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |