http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H07173166-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 |
| filingDate | 1994-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_807cdf8dfdbb58e3b906bde28b86921f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c5c7dc237c167b4b2026a8af2326763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9a84e8ed97f74612715b3be7921ab85 |
| publicationDate | 1995-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H07173166-A |
| titleOfInvention | TAN-1607A derivative, production method and use thereof |
| abstract | (57) [Summary] [Object] To provide a novel compound having squalene synthase inhibitory activity, a method for producing the same, and an antihyperlipidemic agent containing the same. [Structure] General formula (I): (In the formula, X represents an ethylene group or a vinylene group, R 1 , R 2 , R 6 and R 7 each represent hydrogen or an optionally substituted acyl group, and R 3 , R 4 and R 5 each represent a hydroxyl group, an alkoxy group or an optionally substituted amino group. However, when R 1 is an 11-phenyl-10-undecenoyl group, at least one of R 3 , R 4 and R 5 is a group other than a hydroxyl group. ) The compound or its salt represented by this. [Effects] The compound of the present invention has squalene synthase inhibitory activity, has low toxicity, and is effective as a cholesterol-lowering agent, and is therefore useful as a preventive and therapeutic drug for hyperlipidemia. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10653140-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11452291-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5447954-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8513305-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8557864-B2 |
| priorityDate | 1993-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 311.