http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H07165734-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
| filingDate | 1993-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_986453a3b668f3f0c57113a163005b5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8535b7add445df950a545fdaae1da450 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b7aa71ba5053fffbba01e1c7c99f084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b286a0a0f7c941fd0e588822fe5b97ac |
| publicationDate | 1995-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H07165734-A |
| titleOfInvention | Process for producing (+)-3-phenyl-5- {2- (1-pyrrolidinylmethyl) butyryl} isoxazole and salts thereof |
| abstract | (57) [Summary] [Structure] 3-phenyl-5-butyrylisoxazole, pyrrolidine, and formalin were reacted in an alcohol solvent, and the reaction mixture was separated from racemic 3-phenyl-5- {2- ( 1-Pyrrolidinylmethyl) butyryl} isoxazole or a salt thereof is not isolated, but a water-immiscible organic solvent is added to extract the compound, and the organic solvent layer is washed with water, if necessary. (+)-3-phenyl-5- {2- (1-pyrrolidinylmethyl) butyryl} isoxazole and an optically active sulfonic acid is added to the organic solvent layer for optical resolution after dehydration. Method for producing the salt [Effect] It can be resolved with high yield and high optical purity while simplifying the process. |
| priorityDate | 1993-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.