| abstract |
(57) [Summary] [Structure] Formula: [Chemical Formula 1] [Wherein R 1 and R 3 are independently hydrogen, —CH 3 , —C O- (C 1 ~C 6 alkyl), or a -CO-Ar (wherein, Ar is phenyl optionally substituted); selecting R 2 is pyrrolidino, hexamethyleneimino, and from the group consisting of piperidino The present invention provides a pharmaceutical composition for the treatment of a resistant neoplasm, which comprises a compound represented by the formula [1] or a pharmaceutically acceptable salt or solvate thereof. EFFECTS The compositions of the present invention can be used to treat resistant neoplasms in humans or other mammals. |