| abstract |
(57) [Summary] [Structure] A cephalosporin compound represented by the general formula (I). [Chemical 27] In the above formula, Q is nitrogen or CH, P is an acyclic amine or heteroalicyclic amine having one nitrogen atom and one or two hydroxyl groups, preferably N-methyl. -Bis (2-hydroxyethyl) amine, racemic- 3,4-trans-dihydroxy-1-methylpyrrolidine, (3S, 4S) -3,4-dihydroxy-1-methylpyrrolidine, (3R, 4R) -3,4-dihydroxy-1-methylpyrrolidine, meso-3 , 4-dihydroxy-1-methylpyrrolidine, (2S, 4R) -4-hydroxy-1-methyl-2-pyrrolidinemethanol, 3,4 -Cis-dihydroxy-1-methylpiperidine, 3,4 -Trans-dihydroxy-1-methylpiperidine, or tropine. [Effect] The cephalosporin compound of the present invention exhibits excellent antibacterial activity against a wide range of pathogenic bacteria than ceftazidime. |