| abstract |
(57) [Summary] [Structure] The present invention has the general formula [I] [Wherein Ar 1 and Ar 2 are aryl groups and heteroaromatic ring groups; A is a linear saturated or unsaturated aliphatic hydrocarbon group having 3 to 8 carbon atoms; Q is a single bond, -CO-O- , -O- CO -, - CH 2 CH 2 -, - CH = CH -, - OCH 2 -, - SCH 2 -, - CH 2 O -, - CH 2 S-; R 1, R 2 , R 3 and R 4 are hydrogen atom, halogen atom, lower alkyl group, hydroxyl group, lower alkoxy group, aryl group, heteroaromatic ring group; R 5 , R 6 and R 7 are hydrogen atom, lower alkyl group; R 8 Means a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, or an aralkyl group (provided that when Q is a single bond, Ar 1 (R 1 , R 2 ) and Ar 2 And (R 3 and R 4 ) are both 4-chlorophenyl groups}]. [Effect] The compound of the present invention is a novel compound not described in the literature and is useful in the treatment and prevention of hypercholesterolemia, hyperlipidemia and arteriosclerosis. The compounds of the present invention are also useful in treating and preventing fungal infections. |