| abstract |
(57) [Summary] (Correction) [Structure] A peptide containing the amino acid sequence of SEQ ID NO: 1 in the sequence listing and the amino acid sequence at least partially homologous to or similar to the sequence and fragments thereof, DNA encoding the peptide, A method for producing the peptide and a fragment thereof, which comprises the steps of constructing an expression vector by ligating the DNA with a DNA required for expression, transforming a host cell with the expression vector, and culturing the transformed cell. And a therapeutic agent for osteoporosis containing the peptide as an active ingredient. [Effect] It becomes possible to obtain a large amount of a peptide that promotes the differentiation and activation of osteoblasts and preosteoblasts, and to use this to prevent and fundamentally treat osteoporosis. |