| abstract |
(57) [Summary] [Structure] General formula [I] (However, R 1 and R 2 are the same or different and are a hydrogen atom, Represents a hydroxyl group, a cyclo lower alkyloxy group, or a lower alkoxy group which may have a substituent, or forms a lower alkylenedioxy group by being bonded to each other at the terminals, and R 3 has a substituent The optionally substituted nitrogen-containing hetero 6-membered cyclic group, -OR 4 and -OR 5 are the same or different and each represents an optionally protected hydroxyl group. ) An anti-asthma drug comprising a naphthalene derivative or a pharmacologically acceptable salt thereof represented by the formula (1) as an active ingredient. [Effect] The compound [I], which is the active ingredient of the present invention, exhibits an excellent bronchodilator effect, and is therefore useful as a prophylactic / therapeutic agent for asthma. |