| abstract |
(57) [Summary] (Modified) [Objective] To provide an oligonucleotide that is an inhibitor of viral reverse transcriptase. A method of inhibiting a reverse transcriptase in a mammalian cell by supplying an effective amount of the compound to a mammalian cell, and a method of treating a pathological condition in the mammal. (Wherein R is H or a blocking group; A is H, OH, halogen, SH, NH 2 or azide; B Is a nucleoside or deoxynucleoside base; and n and m are integers from 0 to 30) Effect The above compounds can be used for the treatment of diseases caused by viruses. |