| abstract |
(57) [Summary] [Objective] To provide an intermediate which is necessary and important for synthesizing an amidine derivative useful as a therapeutic agent for cardiovascular disease. [Structure] The following general formula: [In the formula, A is an ethylene group in which m hydrogen atoms (m is an integer of 0 to 4) are substituted with an alkyl group having 1 to 6 carbon atoms, and B is n (n is an integer of 0 to 4). It represents an ethylene group or trimethylene group in which a hydrogen atom is substituted with an alkyl group having 1 to 6 carbon atoms. ] The isoquinoline sulfonic acid amide compound shown by these, and its acid addition salt. |