http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0656844-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad3d51747a2eba1e7636894263252df4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D503-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D503-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D503-06 |
| filingDate | 1993-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f47cfcd8fc0650bdd1feff076d89528f |
| publicationDate | 1994-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0656844-A |
| titleOfInvention | Novel alkylene diammonium diclavulanate derivative, process for producing the same and use thereof |
| abstract | (57) [Summary] (Modified) [Objective] To provide a novel alkylene diammonium diclavulanate derivative of the formula (I). The crude clavulanic acid, which is present in the form of an extract in an organic solvent such as alkylene diammonium diclavulanate, ethyl acetate, of the formula: A process for making blanates, optionally isolating the compound of the formula: potassium 2- in isopropanol A method for producing potassium clavulanate by conversion with an alkali alkanoate such as ethylhexanoate. [In the formula, R 1 , R 2 , R 3 and R 4 are H, C 1-8 alkyl group, (substituted) benzyl group, C 2-4 hydroxyalkyl group, etc. or R 1 -R 2 , R 3 -R 4 in (C H 2 ) 3 to 6 and one of the CH 2 is O, S, N R 5 represents H, CH 3 ; n is an integer of 1 to 3] [Effect] The compound of formula (I) has a high β-lactamase inhibitory activity and It exhibits significant synergy in combination with β-lactam antibiotics such as penicillin and cephalosporins. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08511010-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2839955-B2 |
| priorityDate | 1992-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.