abstract |
(57) [Summary] (Modified) [Purpose] Having antagonistic activity against angiotensin II, Provided are novel imidazopyridine derivatives and their salts, which can be used for the treatment of hypertension, aldosteronism, heart failure and elevated intraocular pressure, as well as central nervous system disorders. [Structure] The following formula I [Where R is the following formula R 1 is alkyl, alkenyl, etc., R 2 is H, COOH, For CN, R 3 is COOH, CN, NO 2, etc., R 4 is H Or, Hal and X do not exist, or -NHCO-, -CO NH- and the like, Y represents O or S]. |