| abstract |
(57) [Summary] [Purpose] Providing a novel urokinase inhibitor [Constitution] A compound represented by the following formula (1). [Chemical 1] (In the above formula, R 1 is H, NH 2 , or halogen, R 2, R 3, R 4 , R 5 (R 2 -R 5) at least one of the organic groups containing more than 5 carbon atoms, an organic group containing a sulfur atom or a hydroxy, unsaturated organic group, or a cyclic organic group And each R 2 -R 5 independently represents H, halogen, It is a hydroxy, amino, nitro or organic group, and R 6 and R 7 are each independently H or a linear alkyl group having 1 to 6 carbon atoms. [Effects] The compounds of the present invention are effective for the treatment of urokinase-mediated cell infiltration in mammals. |