abstract |
(57) [Summary] (Modified) [Structure] [Wherein R 1 is alkyl, alkenyl or cycloalkyl, R 2 is hydrogen, halogen or perfluoroalkyl, n is 0, 1, 2 or 3, R 3 is cycloalkyl, R 4 is hydroxyl, alkoxy, etc., R 5 is hydrogen, halogen, nitro, etc., L is cycloalkyl or optionally substituted phenyl, R 6 is A hydroxyl, alkoxy, etc.] propenoyl-imidazole derivative. These compounds are suitable imidazoyl aldehydes and C It is prepared by reaction with H acidic compound and subsequent dehydration of the intermediate. The above-mentioned propenoyl-imidazole derivative can be used as an active compound in a drug for the treatment of arterial hypertension and atherosclerosis. |