| abstract |
(57) [Summary] [Structure] General formula (1) or (2) [Chemical 6] (In the formula, R 1 and R 2 each independently represent a hydrogen atom, an alkanoyl group having 2 to 7 carbon atoms, or -C OCH (OH) CH (C 6 H 5) NHCOC 6 H 5, or -COCH (OH) CH (C 6 H 5) NHCOOC (CH 3) The novel compound represented by 3 represent). The compounds of formula (1) and formula (2) have anti-mitotic activity and anti-tumor activity comparable to those of known taxanes such as taxol or its derivatives. |