http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0640883-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10f6109cdaa2af3eb9893454a209fb81 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-60 |
| filingDate | 1992-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f736a58e2a9c0c08494432affdac1150 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_144bd88bfcedbbaa1c11e566c809964b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3adc68f686bc15f97c239ceec5ad20af |
| publicationDate | 1994-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0640883-A |
| titleOfInvention | Method for producing whitening cosmetics and components thereof |
| abstract | (57) [Summary] [Structure] The whitening cosmetic product of the present invention is characterized in that a glycoside of (+)-catechin is used as a main component of the cosmetic product. The method for producing a whitening cosmetic component of the present invention is a method in which 5,7,3 ′, 4 ′ positions of (+)-catechin are respectively acetylated and, in some cases, 3-position is trimethylsilylated, and a hydroxyl group is an acetyl group. And reacting it with a brominated or fluorinated sugar at the 1-position using various condensing agents, followed by deacetylation to obtain the glycoside of (+)-catechin shown in Chemical formula 1. Characterize. [Chemical 1] [Effect] According to the present invention, the yield is improved three times or more as compared with the conventional method, and the glycoside is successfully synthesized by introducing a method for fluorinating sugar to synthesize (+)-catechin glycoside. However, the yield was greatly improved. In addition, among the synthesized glycosides, tyrosinase inhibitory activity exceeding arbutin was recognized, and it is promising as a component of whitening cosmetics. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9938858-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9429404-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007277100-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0119323-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104292201-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6495524-B1 |
| priorityDate | 1992-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.