| abstract |
(57) [Summary]n[Structure] General formula (I)n[Chemical 1]n [In the formula, R 1 Is a hydrogen atom, lower alkyl group or hydro The xy protecting group is R 2 Is a hydrogen atom or a lower alkyl group To R 3 Is the formula -COR Five (In the formula, R Five Is a hydrogen atom, substitution Optionally having a lower alkyl group, lower alkenyl Group), formula -CO 2 R 6 , Formula-SO 2 R 6 , Formula-CONH R 6 (In the above formula, R 6 Is a lower alkyl group), or a formula- CONH 2 A group represented by Four Is a carboxyl group Is an esterified carboxyl group] A rosporin compound or a pharmaceutically acceptable salt thereof, The manufacturing method and intermediate compounds.n[Effect] The cephalosporin compound of the present invention is Antibacterial activity and digestion against positive and gram-negative bacteria Better absorbability from tubes than conventional ones It is a thing. |