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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
filingDate 1993-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9093b5ee9ac54b4c89d4246810223db7
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publicationDate 1994-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H06329558-A
titleOfInvention Synthetic lipid liposomes
abstract (57) [Summary] [Purpose] To provide a liposome that is stable, can control the targeting direction to a target organ well, and exhibits different pharmacokinetics from conventional ones. [Structure] General formula (I) (In the formula, R means a methyl group or the like. X is a formula -N + (CH 3 ) Means a group represented by 3 · Br − . Where l is It means an integer of 1 to 10. m and n mean the integer of 1-20. ) A drug-containing liposome in which a drug is mixed with a synthetic lipid represented by the formula (1), and a phospholipid may be mixed if necessary. Compared with conventional liposomes, it is characterized by high transferability to organs such as the heart and low transferability to the spleen.
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