| abstract |
(57) [Summary] [Structure] General formula (1) Asp Lys Glu X Val Tyr Phe X His Leu YZ Ile Trp (1) [In the formula, X is Ala or Gly and Y is Asp or Th. r represents Z, which represents Ile, Leu, or γ-methylLeu], and a whitening agent comprising the tetradecapeptides, and a skin cosmetic containing the same. [Effect] The tetradecapeptides (1) have the effect of suppressing the production of melanin and eliminating the pigmentation generated by stimulation with ultraviolet rays, and the cosmetics containing this have an excellent whitening effect and sunburn. It has a preventive and therapeutic effect on spots and freckles due to the above, and is highly safe. |