http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H06316577-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc573488e3baa33251a3d9b0fa9f183b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 |
| filingDate | 1994-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cb08166fe631eac58ffa62f0ebcb1f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c43f08048001d2292ee3547b328c9dd |
| publicationDate | 1994-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H06316577-A |
| titleOfInvention | Ketorolac derivatives with significantly less gastrointestinal irritation and ulcer formation |
| abstract | (57) [Summary] (Modified) [Structure] (±) -5-benzoyl-2,3-dihydro-1H-pyrrolidine-1-carboxylic acid represented by the general formula (I), that is, 2 of ketorolac acid -(1-Pyrrolidinyl) ethyl ester and a pharmaceutically acceptable addition salt thereof, preferably an oxalate salt, and a pharmaceutical composition containing the compound or an addition salt thereof. [Chemical 1] [Effect] Commercial ketorolac (trometamol salt) Is an unwanted side effect (gastrointestinal irritation and ulcer formation) Is known to be. By using the compound of the present invention, this undesirable side effect is significantly reduced, and it is very useful as an analgesic / anti-inflammatory agent. |
| priorityDate | 1993-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.