abstract |
(57) [Summary] (Modified) [Structure] Thienyloxybutenyl derivative having general formula (I) and a pharmacologically acceptable salt thereof, and an anti-ulcer agent containing the compound or a pharmacologically acceptable salt thereof . [Wherein R 1 : 3-8 membered cyclic amino, di C 1 -C 4 alkylamino; R 2 , R 3 : H, C 1 -C 6 alkyl, Substituted C 1 -C 6 alkyl, C 3 -C 6 alkenyl, C 3 -C 6 alkynyl, C 3 -C 6 cycloalkyl, C 6 -C 10 aryl. EFFECT The compounds excellent gastric acid secretion inhibitory action and protective factors enhancing action and Helicobacter pylori (Helicobac It has an excellent antibacterial action against ter pylori ) and is useful as an antiulcer agent. |