| abstract |
(57) [Summary] [Object] An object of the present invention is to provide a production promoter of HGF (Hepatocyte Growth Factor) having an activity of promoting healing of injuries of tissues and organs of a living body. [Structure] The HGF production promoter of the present invention comprises interleukin-1α, interleukin-1β, heparin or a derivative thereof (low molecular weight heparin, etc.), heparan sulfate, prostaglandin E 1 , prostaglandin E 2 , prostaglandin. Gin I 2 , derivatives of these prostaglandins, And at least one selected from the group consisting of clathrates of these prostaglandins or their derivatives as an active ingredient. The HGF production-promoting agent of the present invention has an activity of promoting HGF production in HGF-producing cells, and is therefore useful for wound healing and the like. |