Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5dfc0b033ac4c841466d97a5f28ea32b |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 |
filingDate |
1993-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64cc8165119f8bd2d8719b9a4db7e864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa922a795202e4cbe352709f5714dea2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5614102363015ac325f3c18eef96ba2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbb4df53a0693e6b6585033b0b5290a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4fc29cabf60a799e394410fbc995f33 |
publicationDate |
1994-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H06306074-A |
titleOfInvention |
Antitumor substance BE-32030 |
abstract |
(57) [Summary] (Modified) [Structure] The compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof, the ability to produce the compound of the general formula (I) belonging to the genus Nocardia A method for producing a compound represented by the general formula (I), which comprises culturing a microorganism having the same and collecting the compound from the culture, and an antitumor comprising the compound or a pharmaceutically acceptable salt thereof as an active ingredient. Agents, and microorganisms belonging to the genus Nocardia or mutants thereof that have the ability to produce compounds of general formula (I). [Wherein R 1 is H or OH; R 2 is a group — (CH 2 ) p CH 3 or - (CH 2) q CH = CH (CH 2) 7 CH 3 ; p is 10 or 12; q is 3 or 5; [Effects] The BE-32030 compounds represented by the general formula (I) have strong inhibitory effects on mouse and human cancer cells, and are therefore useful as therapeutic agents for cancer in the field of medicine. Is. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112158886-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2014132902-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014132902-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5811440-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5919671-A |
priorityDate |
1993-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |