| abstract |
(57) [Summary] [Structure] Granules obtained by sonicating a mixed lipid in which the phospholipid and the nonionic polyoxyethylene-based surfactant have a molar ratio of 5/95 to 95/5 in an aqueous solution. Diameter 1 0 to 3000 angstrom, particle size variation 10 % Or less of W / O / W mixed lipid membrane vesicles. [Effect] Mixed lipid membrane vesicles with a small particle size variation generated at a specific component ratio of phospholipids and nonionic polyoxyethylene-based surfactants, and the type of drug embedded in the vesicles. The particle size can be controlled depending on the amount, the amount or the purpose. Cosmetics containing this mixed lipid membrane vesicle are substances with excellent skin cell affinity, A skin activator carrier by mixed lipid membrane vesicles is obtained. |