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filingDate 1993-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_621486b8a6d4b1c424873c7de7a006e4
publicationDate 1994-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H06289017-A
titleOfInvention Method for determining DNA base sequence and measuring device for determining DNA base sequence
abstract (57) [Summary] [PROBLEMS] To provide a method for determining a DNA base sequence using a scanning probe microscope and a measuring device for determining a DNA base sequence. [Constitution] A measuring device for determining a nucleotide sequence of DNA is a scanning probe microscope and a probe 2 of the scanning probe microscope. And a solution cell 4 for containing the single-stranded DNA to be measured, Solution inlet / outlet 5 and outlet 6 provided in the solution cell 4 And the solution tanks 14, 15 connected to the entrance 5 It consists of 16. DNA image when a solution containing no base or DNA fragment is introduced, and the above-mentioned base or DN By comparing with the DNA image when the solution containing the A fragment was introduced, the nucleotide sequence of the DNA can be read easily, quickly, and using a small amount of sample. The scanning probe microscope is preferably a scanning tunneling microscope or an atomic force microscope.
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