http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H06279443-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 |
| filingDate | 1994-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b341dd8eae3b7c0c4efba0f6b8c60ebb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_defa8bfcd8eb71511381f7f94d7f2886 |
| publicationDate | 1994-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H06279443-A |
| titleOfInvention | 6'-homoneplanocin A derivative and method for producing the same |
| abstract | (57) [Summary] (Modified) 6'-homoneplanocin A derivative represented by the general formula 1 or a non-toxic salt thereof, a process for producing the same, and a compound represented by the general formula 2, which is an intermediate thereof, and the general formula It is a cyclopentene derivative represented by 3. (In the formula, A represents CH or N. R 1 , R 2 and R Each 3 independently or together represents a hydroxyl-protecting group, and R 4 represents a hydrogen atom or an amino-protecting group. Y represents an electron-withdrawing leaving group, a hydroxyl group or an acyloxy group. [Effect] The 6'-homoneplanocin A derivative (1) and its non-toxic salt show excellent antiviral activity, and moreover, its cytotoxicity is extremely low as compared with neplanocin A, Its chemotherapeutic coefficient is extremely large, and it is useful as a highly safe antiviral agent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002510691-A |
| priorityDate | 1993-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.