abstract |
(57) [Summary] [Structure] General formula: MWYAQ [wherein M is the formula: (Wherein R 1 and R 2 are each hydrogen or the like, Z is S or O respectively), W is a bond, lower alkylene or the like, Y is a lower alkylene, or Etc. A is a bond or lower alkylene and Q is of the formula: (Wherein R 4 represents lower alkyl, etc.) and the like, and a pharmaceutically acceptable salt thereof. [Effect] Since this compound has a strong acetylcholinesterase inhibitory activity, it is useful for the prevention and treatment of central nervous system diseases such as amnesia and dementia. |